Clinical Scorecard: In Research, Diversity Matters

At a Glance

Key Highlights

• Diverse populations in clinical research improve understanding of treatment responses.
• Black and Hispanic populations are underrepresented despite higher prevalence of certain eye disorders.
• Community engagement and trust-building are essential for increasing trial participation.
• Historical mistreatment contributes to mistrust in clinical research among minorities.
• Effective recruitment strategies include engaging community leaders and providing direct access to care.

Guideline-Based Recommendations

Diagnosis

• Assess demographic characteristics affecting treatment response.

Management

• Implement diversity action plans for clinical studies as required by the FDA.

Monitoring & Follow-up

• Continuously evaluate enrollment strategies to ensure representation of diverse populations.

Risks

• Address potential mistrust and barriers to participation in clinical trials.

Patient & Prescribing Data

Racial and ethnic minorities, particularly those with comorbidities or living in rural areas.

Community-based approaches can enhance trust and increase participation in clinical trials.

Clinical Best Practices

• Engage community leaders to build trust and facilitate patient recruitment.
• Educate all clinical staff on the importance of diversity in clinical research.
• Utilize portable equipment for screenings in underserved areas to improve access.

References

• FDA Diversity Action Plans
• Wagner Kapoor Institute Outreach Program