4 Topic Commentaries

Peptide eye drop could offer a noninvasive alternative to injections for nAMD treatment 

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  Patricia Becerra, Ph.D.

  Retinal biochemistry and vision science

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  National Eye Institute, National Institutes of Health

  While not a cure, this study shows that PEDF-based eye drops can slow progression of a variety of degenerative retinal diseases in animals, including various types of retinitis pigmentosa and dry age-related macular degeneration (AMD). — verbatim from source

  Source
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  Alexandra Bernardo-Colón, Ph.D.

  Vision science and retinal research

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  National Eye Institute, National Institutes of Health

  For the first time, we show that eye drops containing these short peptides can pass into the eye and have a therapeutic effect on the retina. — verbatim from source

  Source
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  Laura Ensign, Ph.D.

  Ocular drug delivery and biomedical engineering

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  Wilmer Eye Institute, Johns Hopkins Medicine

  The main problem with conventional liquid eye drops is that they are very short lasting and not very much drug gets into the eye because the watery substance is blinked away quickly. — verbatim from source

  Source
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  Carol M. Troy, MD, PhD

  Neurology; pathology & cell biology (retinal vascular disease research)

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  Columbia University Vagelos College of Physicians and Surgeons

  Anti-VEGF therapy has helped a lot of people with RVO, but the fear factor—having to get a needle in the eye—causes many people to delay treatment, which can lead to retinal damage. There’s an opportunity to help more people with this disease that is a leading cause of blindness worldwide. — verbatim from source

  Source