Home OCT and Modeling May Reduce Trial Sizes

Home OCT with PK/PD modeling achieved the same power as traditional biweekly, on-site monitoring with only 33 to 35 patients per arm

By: Sarah Fackler, managing editor, Optometric Management

Retinal Physician November 18, 2025 Vol 22, Issue November/December 2025

Clinical Report: Home OCT and Modeling May Reduce Trial Sizes

{'add': 'Specify how statistical power is maintained despite reduced sample size.'}

{'add': 'Examples of traditional monitoring methods.'}

{'format': 'Consider using bullet points for clarity.'}

{'add': "Details on Monte Carlo simulations' implications."}

{'expand': 'How home monitoring enhances patient engagement.'}

{'add': 'Challenges or limitations of home OCT implementation.'}